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Administration of Myelin Basic Protein Peptides Encapsulated in Mannosylated Liposomes Normalizes Level of Serum TNF-α and IL-2 and Chemoattractants CCL2 and CCL4 in Multiple Sclerosis Patients

We have previously shown that immunodominant MBP peptides encapsulated in mannosylated liposomes (Xemys) effectively suppressed experimental allergic encephalomyelitis (EAE). Within the frames of the successfully completed phase I clinical trial, we investigated changes in the serum cytokine profile...

詳細記述

保存先:
書誌詳細
出版年:Mediators Inflamm
主要な著者: Lomakin, Yakov, Belogurov, Alexey, Glagoleva, Irina, Stepanov, Alexey, Zakharov, Konstantin, Okunola, John, Smirnov, Ivan, Genkin, Dmitry, Gabibov, Alexander
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi Publishing Corporation 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864531/
https://ncbi.nlm.nih.gov/pubmed/27239100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2847232
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