Tag7 (PGLYRP1) in Complex with Hsp70 Induces Alternative Cytotoxic Processes in Tumor Cells via TNFR1 Receptor

Tag7 (also known as peptidoglycan recognition protein PGRP-S, PGLYRP1), an innate immunity protein, interacts with Hsp70 to form a stable Tag7-Hsp70 complex with cytotoxic activity against some tumor cell lines. In this study, we have analyzed the programmed cell death mechanisms that are induced wh...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Yashin, Denis V., Ivanova, Olga K., Soshnikova, Natalia V., Sheludchenkov, Anton A., Romanova, Elena A., Dukhanina, Elena A., Tonevitsky, Alexander G., Gnuchev, Nikolai V., Gabibov, Alexander G., Georgiev, Georgii P., Sashchenko, Lidia P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571894/
https://ncbi.nlm.nih.gov/pubmed/26183779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.639732
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