Tag7 (PGLYRP1) in Complex with Hsp70 Induces Alternative Cytotoxic Processes in Tumor Cells via TNFR1 Receptor

Tag7 (also known as peptidoglycan recognition protein PGRP-S, PGLYRP1), an innate immunity protein, interacts with Hsp70 to form a stable Tag7-Hsp70 complex with cytotoxic activity against some tumor cell lines. In this study, we have analyzed the programmed cell death mechanisms that are induced wh...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Yashin, Denis V., Ivanova, Olga K., Soshnikova, Natalia V., Sheludchenkov, Anton A., Romanova, Elena A., Dukhanina, Elena A., Tonevitsky, Alexander G., Gnuchev, Nikolai V., Gabibov, Alexander G., Georgiev, Georgii P., Sashchenko, Lidia P.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2015
Sujets:
Cell Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571894/
https://ncbi.nlm.nih.gov/pubmed/26183779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.639732
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