A 8-mer Peptide of PGLYRP1/Tag7 Innate Immunity Protein Binds to TNFR1 Receptor and Inhibits TNFα-Induced Cytotoxic Effect and Inflammation

Search for novel regulatory protein fragments with potential functional roles is required both for understanding the immune response mechanisms and the development of targeted immunotherapy. Earlier we demonstrated that the PGLYRP1/Tag7 innate immunity protein can be regarded as an inhibitor of TNFα...

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Pubblicato in:Front Immunol
Autori principali: Telegin, Georgii B., Chernov, Aleksandr S., Kazakov, Vitaly A., Romanova, Elena A., Sharapova, Tatiana N., Yashin, Denis V., Gabibov, Alexander G., Sashchenko, Lidia P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215708/
https://ncbi.nlm.nih.gov/pubmed/34163464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.622471
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