A 8-mer Peptide of PGLYRP1/Tag7 Innate Immunity Protein Binds to TNFR1 Receptor and Inhibits TNFα-Induced Cytotoxic Effect and Inflammation

Search for novel regulatory protein fragments with potential functional roles is required both for understanding the immune response mechanisms and the development of targeted immunotherapy. Earlier we demonstrated that the PGLYRP1/Tag7 innate immunity protein can be regarded as an inhibitor of TNFα...

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Udgivet i:Front Immunol
Main Authors: Telegin, Georgii B., Chernov, Aleksandr S., Kazakov, Vitaly A., Romanova, Elena A., Sharapova, Tatiana N., Yashin, Denis V., Gabibov, Alexander G., Sashchenko, Lidia P.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215708/
https://ncbi.nlm.nih.gov/pubmed/34163464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.622471
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