Nucleic acids in chemistry and biology.-

Por Blackburn, G. Michael;, Gait, Michael J.
Publicado em 1996

TWO HYDROLASE RESISTANT ANALOGUES OF DIADENOSINE 5′,5′″-P(1),P(3)-TRIPHOSPHATE FOR STUDIES WITH FHIT, THE HUMAN FRAGILE HISTIDINE TRIAD PROTEIN

Por Blackburn, G. Michael, Liu, Xiaohai, Rösler, Angelika, Brenner, Charles
Publicado em 1998

Photoproducts from DNA pyrimidine bases and polycyclic aromatic hydrocarbons

Por Blackburn, G. Michael, Fenwick, R. G., Lockwood, G., Williams, G. M.
Publicado em 1977

ATP analogues with modified phosphate chains and their selectivity for rat P2X(2) and P2X(2/3) receptors

Por Spelta, Valeria, Mekhalfia, Abdelaziz, Rejman, Dominik, Thompson, Mark, Blackburn, G Michael, North, R Alan
Publicado em 2003

(19)F NMR and DFT Analysis Reveal Structural and Electronic Transition State Features for RhoA‐Catalyzed GTP Hydrolysis

Por Jin, Yi, Molt, Robert W., Waltho, Jonathan P., Richards, Nigel G. J., Blackburn, G. Michael
Publicado no Angew Chem Int Ed Engl (2016)

P(1),P(4)-Dithio-P(2),P(3)-monochloromethylene diadenosine 5′,5‴-P(1),P(4)-tetraphosphate: A novel antiplatelet agent

Por Chan, Samuel W., Gallo, Steven J., Kim, Byung K., Guo, Mao J., Blackburn, G. Michael, Zamecnik, Paul C.
Publicado em 1997

Uracil-DNA glycosylase–DNA substrate and product structures: Conformational strain promotes catalytic efficiency by coupled stereoelectronic effects

Por Parikh, Sudip S., Walcher, Gunter, Jones, Garry D., Slupphaug, Geir, Krokan, Hans E., Blackburn, G. Michael, Tainer, John A.
Publicado em 2000

X-ray crystallographic studies reveal that the incorporation of spacer groups in carbonic anhydrase inhibitors causes alternate binding modes

Por Fisher, S. Zoë, Govindasamy, Lakshmanan, Boyle, Nicholas, Agbandje-McKenna, Mavis, Silverman, David N., Blackburn, G. Michael, McKenna, Robert
Publicado em 2006

Biochemical, Crystallographic and Mutagenic Characterization of Hint, the AMP-Lysine Hydrolase, with Novel Substrates and Inhibitors

Por Krakowiak, Agnieszka, Pace, Helen C., Blackburn, G. Michael, Adams, Martina, Mekhalfia, Abdelaziz, Kaczmarek, Renata, Baraniak, Janina, Stec, Wojciech J., Brenner, Charles
Publicado em 2004

A Trojan horse transition state analogue generated by MgF(3)(−) formation in an enzyme active site

Por Baxter, Nicola J., Olguin, Luis F., Goličnik, Marko, Feng, Guoqiang, Hounslow, Andrea M., Bermel, Wolfgang, Blackburn, G. Michael, Hollfelder, Florian, Waltho, Jonathan P., Williams, Nicholas H.
Publicado em 2006

Purification and crystallization of complexes modeling the active state of the fragile histidine triad protein

Por Brenner, Charles, Pace, Helen C., Garrison, Preston N., Robinson, Angela K., Rosler, Angelika, Liu, Xiao-Hai, Blackburn, G.Michael, Croce, Carlo M., Huebner, Kay, Barnes, Larry D.
Publicado em 1997

α-Fluorophosphonates reveal how a phosphomutase conserves transition state conformation over hexose recognition in its two-step reaction

Por Jin, Yi, Bhattasali, Debabrata, Pellegrini, Erika, Forget, Stephanie M., Baxter, Nicola J., Cliff, Matthew J., Bowler, Matthew W., Jakeman, David L., Blackburn, G. Michael, Waltho, Jonathan P.
Publicado em 2014

Genetic, biochemical, and crystallographic characterization of Fhit–substrate complexes as the active signaling form of Fhit

Por Pace, Helen C., Garrison, Preston N., Robinson, Angela K., Barnes, Larry D., Draganescu, Alexandra, Rösler, Angelika, Blackburn, G. Michael, Siprashvili, Zurab, Croce, Carlo M., Huebner, Kay, Brenner, Charles
Publicado em 1998

Atomic details of near-transition state conformers for enzyme phosphoryl transfer revealed by [Formula: see text] rather than by phosphoranes

Por Baxter, Nicola J., Bowler, Matthew W., Alizadeh, Tooba, Cliff, Matthew J., Hounslow, Andrea M., Wu, Bin, Berkowitz, David B., Williams, Nicholas H., Blackburn, G. Michael, Waltho, Jonathan P.
Publicado em 2010

Near attack conformers dominate β-phosphoglucomutase complexes where geometry and charge distribution reflect those of substrate

Por Griffin, Joanna L., Bowler, Matthew W., Baxter, Nicola J., Leigh, Katherine N., Dannatt, Hugh R. W., Hounslow, Andrea M., Blackburn, G. Michael, Webster, Charles Edwin, Cliff, Matthew J., Waltho, Jonathan P.
Publicado em 2012

Robotic QM/MM-driven maturation of antibody combining sites

Por Smirnov, Ivan V., Golovin, Andrey V., Chatziefthimiou, Spyros D., Stepanova, Anastasiya V., Peng, Yingjie, Zolotareva, Olga I., Belogurov, Alexey A., Kurkova, Inna N., Ponomarenko, Natalie A., Wilmanns, Matthias, Blackburn, G. Michael, Gabibov, Alexander G., Lerner, Richard A.
Publicado no Sci Adv (2016)

Chemical polysialylation of human recombinant butyrylcholinesterase delivers a long-acting bioscavenger for nerve agents in vivo

Por Ilyushin, Denis G., Smirnov, Ivan V., Belogurov, Alexey A., Dyachenko, Igor A., Zharmukhamedova, Tatiana Iu., Novozhilova, Tatjana I., Bychikhin, Eugene A., Serebryakova, Marina V., Kharybin, Oleg N., Murashev, Arkadii N., Anikienko, Konstantin A., Nikolaev, Eugene N., Ponomarenko, Natalia A., Genkin, Dmitry D., Blackburn, G. Michael, Masson, Patrick, Gabibov, Alexander G.
Publicado em 2013