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TWO HYDROLASE RESISTANT ANALOGUES OF DIADENOSINE 5′,5′″-P(1),P(3)-TRIPHOSPHATE FOR STUDIES WITH FHIT, THE HUMAN FRAGILE HISTIDINE TRIAD PROTEIN

The design and synthesis of analogues of diadenosine 5′,5′″-P(1),P(3)-triphosphate that are resistant to pyrophosphate hydrolysis is described in relation to their role in signaling and tumorigenesis involving the Fhit protein, the human fragile histidine triad protein, which is a novel Ap3A binding...

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Detalhes bibliográficos
Main Authors: Blackburn, G. Michael, Liu, Xiaohai, Rösler, Angelika, Brenner, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556045/
https://ncbi.nlm.nih.gov/pubmed/9708352
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