Correlation of Fragile Histidine Triad (Fhit) Protein Structural Features with Effector Interactions and Biological Functions

We have previously shown that Fhit tumor suppressor protein interacts with Hsp60 chaperone machinery and ferredoxin reductase (Fdxr) protein. Fhit-effector interactions are associated with a Fhit-dependent increase in Fdxr stability, followed by generation of reactive oxygen species and apoptosis in...

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Bibliografiske detaljer
Main Authors: Pichiorri, Flavia, Okumura, Hiroshi, Nakamura, Tatsuya, Garrison, Preston N., Gasparini, Pierluigi, Suh, Sung-Suk, Druck, Teresa, McCorkell, Kelly A., Barnes, Larry D., Croce, Carlo M., Huebner, Kay
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Mechanisms of Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613607/
https://ncbi.nlm.nih.gov/pubmed/19004824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806638200
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