Correlation of Fragile Histidine Triad (Fhit) Protein Structural Features with Effector Interactions and Biological Functions

We have previously shown that Fhit tumor suppressor protein interacts with Hsp60 chaperone machinery and ferredoxin reductase (Fdxr) protein. Fhit-effector interactions are associated with a Fhit-dependent increase in Fdxr stability, followed by generation of reactive oxygen species and apoptosis in...

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Detalhes bibliográficos
Main Authors: Pichiorri, Flavia, Okumura, Hiroshi, Nakamura, Tatsuya, Garrison, Preston N., Gasparini, Pierluigi, Suh, Sung-Suk, Druck, Teresa, McCorkell, Kelly A., Barnes, Larry D., Croce, Carlo M., Huebner, Kay
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613607/
https://ncbi.nlm.nih.gov/pubmed/19004824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806638200
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