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Loss of fragile histidine triad (Fhit) protein expression alters the translation of cancer-associated mRNAs

OBJECTIVES: In > 50% of cancers tumor development involves the early loss of Fhit (fragile histidine triad) protein expression, yet the mechanistic pathway(s) by which Fhit mediates its tumor suppressor functions are not fully understood. Earlier attempts to identify a Fhit-deficient gene express...

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Detalhes bibliográficos
Publicado no:BMC Res Notes
Main Authors: Kiss, Daniel L., Baez, William D., Huebner, Kay, Bundschuh, Ralf, Schoenberg, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853088/
https://ncbi.nlm.nih.gov/pubmed/29540221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-018-3278-9
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