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Restoration of fragile histidine triad (FHIT) expression induces apoptosis and suppresses tumorigenicity in lung and cervical cancer cell lines

Loss of expression of the Fhit protein is often associated with the development of many human epithelial cancers, including lung and cervical carcinomas. Restoration of Fhit expression in cell lines derived from these tumors has however yielded conflicting results, prompting the need for careful eva...

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Detalhes bibliográficos
Main Authors: Roz, Luca, Gramegna, Marcella, Ishii, Hideshi, Croce, Carlo M., Sozzi, Gabriella
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122572/
https://ncbi.nlm.nih.gov/pubmed/11891319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.062030799
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