P(1),P(4)-Dithio-P(2),P(3)-monochloromethylene diadenosine 5′,5‴-P(1),P(4)-tetraphosphate: A novel antiplatelet agent

We have previously demonstrated in a series of searches for antithrombotic agents that diadenosine 5′,5‴-P(1),P(4)-tetraphosphate (AppppA) and its analogues are competitive inhibitors of ADP-induced platelet aggregation. Among various analogues, the P(2),P(3)-monochloromethylene analog of AppppA (Ap...

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Hlavní autoři: Chan, Samuel W., Gallo, Steven J., Kim, Byung K., Guo, Mao J., Blackburn, G. Michael, Zamecnik, Paul C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences of the USA 1997
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC20563/
https://ncbi.nlm.nih.gov/pubmed/9108100
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