Role of κ→λ light-chain constant-domain switch in the structure and functionality of A17 reactibody

The engineering of catalytic function in antibodies requires precise information on their structure. Here, results are presented that show how the antibody domain structure affects its functionality. The previously designed organophos­phate-metabolizing reactibody A17 has been re-engineered by repla...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ponomarenko, Natalia, Chatziefthimiou, Spyros D., Kurkova, Inna, Mokrushina, Yuliana, Stepanova, Anastasiya, Smirnov, Ivan, Avakyan, Marat, Bobik, Tatyana, Mamedov, Azad, Mitkevich, Vladimir, Belogurov, Alexey, Fedorova, Olga S., Dubina, Michael, Golovin, Andrey, Lamzin, Victor, Friboulet, Alain, Makarov, Alexander A., Wilmanns, Matthias, Gabibov, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2014
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949517/
https://ncbi.nlm.nih.gov/pubmed/24598740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004713032446
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados