Models of β-amyloid induced Tau-pathology: the long and “folded” road to understand the mechanism

অনুযায়ী Stancu, Ilie-Cosmin, Vasconcelos, Bruno, Terwel, Dick, Dewachter, Ilse
প্রকাশিত Mol Neurodegener (2014)

Amyloid Activates GSK-3β to Aggravate Neuronal Tauopathy in Bigenic Mice

অনুযায়ী Terwel, Dick, Muyllaert, David, Dewachter, Ilse, Borghgraef, Peter, Croes, Sophie, Devijver, Herman, Van Leuven, Fred
প্রকাশিত 2008

Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice

অনুযায়ী Heneka, Michael T, Sastre, Magdalena, Dumitrescu-Ozimek, Lucia, Dewachter, Ilse, Walter, Jochen, Klockgether, Thomas, Van Leuven, Fred
প্রকাশিত 2005

β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Increases Amyloid Deposition in Brain Parenchyma but Reduces Cerebrovascular Amyloid Angiopathy in Aging BACE × APP[V717I] Double...

অনুযায়ী Willem, Michael, Dewachter, Ilse, Smyth, Neil, Van Dooren, Tom, Borghgraef, Peter, Haass, Christian, Van Leuven, Fred
প্রকাশিত 2004

Neurodegeneration and Neuroinflammation in cdk5/p25-Inducible Mice : A Model for Hippocampal Sclerosis and Neocortical Degeneration

অনুযায়ী Muyllaert, David, Terwel, Dick, Kremer, Anna, Sennvik, Kristina, Borghgraef, Peter, Devijver, Herman, Dewachter, Ilse, Van Leuven, Fred
প্রকাশিত 2008

Nonsteroidal Anti-Inflammatory Drugs and Peroxisome Proliferator-Activated Receptor-γ Agonists Modulate Immunostimulated Processing of Amyloid Precursor Protein through Regulation...

অনুযায়ী Sastre, Magdalena, Dewachter, Ilse, Landreth, Gary E., Willson, Timothy M., Klockgether, Thomas, van Leuven, Fred, Heneka, Michael T.
প্রকাশিত J Neurosci (2003)

Glycines from the APP GXXXG/GXXXA Transmembrane Motifs Promote Formation of Pathogenic Aβ Oligomers in Cells

অনুযায়ী Decock, Marie, Stanga, Serena, Octave, Jean-Noël, Dewachter, Ilse, Smith, Steven O., Constantinescu, Stefan N., Kienlen-Campard, Pascal
প্রকাশিত Front Aging Neurosci (2016)

Activation of phagocytic activity in astrocytes by reduced expression of the inflammasome component ASC and its implication in a mouse model of Alzheimer disease

অনুযায়ী Couturier, Julien, Stancu, Ilie-Cosmin, Schakman, Olivier, Pierrot, Nathalie, Huaux, François, Kienlen-Campard, Pascal, Dewachter, Ilse, Octave, Jean-Noël
প্রকাশিত J Neuroinflammation (2016)

Beta-site amyloid precursor protein-cleaving enzyme-1 (BACE1)-mediated changes of endogenous amyloid beta in wild-type and transgenic mice in vivo

অনুযায়ী Hirata-Fukae, Chiho, Sidahmed, Elkhansa Hassan, Gooskens, Thomas P., Aisen, Paul S., Dewachter, Ilse, Devijver, Herman, Van Leuven, Fred, Matsuoka, Yasuji
প্রকাশিত 2008

Neurological characterization of mice deficient in GSK3α highlight pleiotropic physiological functions in cognition and pathological activity as Tau kinase

অনুযায়ী Maurin, Hervé, Lechat, Benoit, Dewachter, Ilse, Ris, Laurence, Louis, Justin V, Borghgraef, Peter, Devijver, Herman, Jaworski, Tomasz, Van Leuven, Fred
প্রকাশিত 2013

Neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) slows down Alzheimer's disease-like pathology in amyloid precursor protein-transgenic mice

অনুযায়ী Rat, Dorothea, Schmitt, Ulrich, Tippmann, Frank, Dewachter, Ilse, Theunis, Clara, Wieczerzak, Ewa, Postina, Rolf, van Leuven, Fred, Fahrenholz, Falk, Kojro, Elzbieta
প্রকাশিত 2011

Analysis by a highly sensitive split luciferase assay of the regions involved in APP dimerization and its impact on processing

অনুযায়ী Decock, Marie, El Haylani, Laetitia, Stanga, Serena, Dewachter, Ilse, Octave, Jean-Noël, Smith, Steven O., Constantinescu, Stefan N., Kienlen-Campard, Pascal
প্রকাশিত FEBS Open Bio (2015)

Neuronal or Glial Expression of Human Apolipoprotein E4 Affects Parenchymal and Vascular Amyloid Pathology Differentially in Different Brain Regions of Double- and Triple-Transgeni...

অনুযায়ী Van Dooren, Tom, Muyllaert, David, Borghgraef, Peter, Cresens, Annelies, Devijver, Herman, Van der Auwera, Ingrid, Wera, Stefaan, Dewachter, Ilse, Van Leuven, Fred
প্রকাশিত 2006

Aging Increased Amyloid Peptide and Caused Amyloid Plaques in Brain of Old APP/V717I Transgenic Mice by a Different Mechanism than Mutant Presenilin1

অনুযায়ী Dewachter, Ilse, Van Dorpe, Jo, Smeijers, Liesbet, Gilis, Martine, Kuipéri, Cuno, Laenen, Isabelle, Caluwaerts, Nathalie, Moechars, Dieder, Checler, Frédéric, Vanderstichele, Hugo, Van Leuven, Fred
প্রকাশিত J Neurosci (2000)

Presenilin Transmembrane Domain 8 Conserved AXXXAXXXG Motifs Are Required for the Activity of the γ-Secretase Complex

অনুযায়ী Marinangeli, Claudia, Tasiaux, Bernadette, Opsomer, Rémi, Hage, Salim, Sodero, Alejandro O., Dewachter, Ilse, Octave, Jean Noël, Smith, Steven O., Constantinescu, Stefan N., Kienlen-Campard, Pascal
প্রকাশিত J Biol Chem (2015)

AAV-Tau Mediates Pyramidal Neurodegeneration by Cell-Cycle Re-Entry without Neurofibrillary Tangle Formation in Wild-Type Mice

অনুযায়ী Jaworski, Tomasz, Dewachter, Ilse, Lechat, Benoit, Croes, Sophie, Termont, Annelies, Demedts, David, Borghgraef, Peter, Devijver, Herman, Filipkowski, Robert K., Kaczmarek, Leszek, Kügler, Sebastian, Van Leuven, Fred
প্রকাশিত 2009

What is the evidence that tau pathology spreads through prion-like propagation?

অনুযায়ী Mudher, Amrit, Colin, Morvane, Dujardin, Simon, Medina, Miguel, Dewachter, Ilse, Naini, Seyedeh Maryam Alavi, Mandelkow, Eva-Maria, Mandelkow, Eckhard, Buée, Luc, Goedert, Michel, Brion, Jean-Pierre
প্রকাশিত Acta Neuropathol Commun (2017)

Aggregated Tau activates NLRP3–ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo

অনুযায়ী Stancu, Ilie-Cosmin, Cremers, Niels, Vanrusselt, Hannah, Couturier, Julien, Vanoosthuyse, Alexandre, Kessels, Sofie, Lodder, Chritica, Brône, Bert, Huaux, François, Octave, Jean-Noël, Terwel, Dick, Dewachter, Ilse
প্রকাশিত Acta Neuropathol (2019)

Presenilin 2-Dependent Maintenance of Mitochondrial Oxidative Capacity and Morphology

অনুযায়ী Contino, Sabrina, Porporato, Paolo E., Bird, Matthew, Marinangeli, Claudia, Opsomer, Rémi, Sonveaux, Pierre, Bontemps, Françoise, Dewachter, Ilse, Octave, Jean-Noël, Bertrand, Luc, Stanga, Serena, Kienlen-Campard, Pascal
প্রকাশিত Front Physiol (2017)

Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo

অনুযায়ী Vasconcelos, Bruno, Stancu, Ilie-Cosmin, Buist, Arjan, Bird, Matthew, Wang, Peng, Vanoosthuyse, Alexandre, Van Kolen, Kristof, Verheyen, An, Kienlen-Campard, Pascal, Octave, Jean-Noël, Baatsen, Peter, Moechars, Diederik, Dewachter, Ilse
প্রকাশিত Acta Neuropathol (2016)