Presenilin 2-Dependent Maintenance of Mitochondrial Oxidative Capacity and Morphology

Mitochondrial dysfunction plays a pivotal role in the progression of Alzheimer's disease (AD), and yet the mechanisms underlying the impairment of mitochondrial function in AD remain elusive. Recent evidence suggested a role for Presenilins (PS1 or PS2) in mitochondrial function. Mutations of P...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Contino, Sabrina, Porporato, Paolo E., Bird, Matthew, Marinangeli, Claudia, Opsomer, Rémi, Sonveaux, Pierre, Bontemps, Françoise, Dewachter, Ilse, Octave, Jean-Noël, Bertrand, Luc, Stanga, Serena, Kienlen-Campard, Pascal
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650731/
https://ncbi.nlm.nih.gov/pubmed/29085303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00796
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