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Neurodegeneration and Neuroinflammation in cdk5/p25-Inducible Mice : A Model for Hippocampal Sclerosis and Neocortical Degeneration
The cyclin-dependent kinase cdk5 is atypically active in postmitotic neurons and enigmatic among the kinases proposed as molecular actors in neurodegeneration. We generated transgenic mice to express p25, the N-terminally truncated p35 activator of cdk5, in forebrain under tetracycline control (TET-...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Investigative Pathology
2008
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2312368/ https://ncbi.nlm.nih.gov/pubmed/18202185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070693 |
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