Early Improved and Late Defective Cognition Is Reflected by Dendritic Spines in Tau.P301L Mice

Cognitive demise correlates with progressive brain tauopathy in dementing patients. Improved cognition of young Tau.P301L mice contrasts with dysfunction later in life and remains unexplained (Boekhoorn et al., 2006). To unravel early mechanisms, we composed a correlative time line of clinical sympt...

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Vydáno v:J Neurosci
Hlavní autoři: Kremer, Anna, Maurin, Hervé, Demedts, David, Devijver, Herman, Borghgraef, Peter, Van Leuven, Fred
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6634152/
https://ncbi.nlm.nih.gov/pubmed/22159117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4859-11.2011
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