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Early Improved and Late Defective Cognition Is Reflected by Dendritic Spines in Tau.P301L Mice
Cognitive demise correlates with progressive brain tauopathy in dementing patients. Improved cognition of young Tau.P301L mice contrasts with dysfunction later in life and remains unexplained (Boekhoorn et al., 2006). To unravel early mechanisms, we composed a correlative time line of clinical sympt...
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| Veröffentlicht in: | J Neurosci |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6634152/ https://ncbi.nlm.nih.gov/pubmed/22159117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4859-11.2011 |
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