AAV-Tau Mediates Pyramidal Neurodegeneration by Cell-Cycle Re-Entry without Neurofibrillary Tangle Formation in Wild-Type Mice

In Alzheimer's disease tauopathy is considered secondary to amyloid, and the duality obscures their relation and the definition of their respective contributions. Transgenic mouse models do not resolve this problem conclusively, i.e. the relative hierarchy of amyloid and tau pathology depends o...

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Bibliografski detalji
Glavni autori: Jaworski, Tomasz, Dewachter, Ilse, Lechat, Benoit, Croes, Sophie, Termont, Annelies, Demedts, David, Borghgraef, Peter, Devijver, Herman, Filipkowski, Robert K., Kaczmarek, Leszek, Kügler, Sebastian, Van Leuven, Fred
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748684/
https://ncbi.nlm.nih.gov/pubmed/19794916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007280
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