AAV-Tau Mediates Pyramidal Neurodegeneration by Cell-Cycle Re-Entry without Neurofibrillary Tangle Formation in Wild-Type Mice

In Alzheimer's disease tauopathy is considered secondary to amyloid, and the duality obscures their relation and the definition of their respective contributions. Transgenic mouse models do not resolve this problem conclusively, i.e. the relative hierarchy of amyloid and tau pathology depends o...

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Detalhes bibliográficos
Main Authors: Jaworski, Tomasz, Dewachter, Ilse, Lechat, Benoit, Croes, Sophie, Termont, Annelies, Demedts, David, Borghgraef, Peter, Devijver, Herman, Filipkowski, Robert K., Kaczmarek, Leszek, Kügler, Sebastian, Van Leuven, Fred
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748684/
https://ncbi.nlm.nih.gov/pubmed/19794916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007280
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