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What is the evidence that tau pathology spreads through prion-like propagation?

Emerging experimental evidence suggests that the spread of tau pathology in the brain in Tauopathies reflects the propagation of abnormal tau species along neuroanatomically connected brain areas. This propagation could occur through a “prion-like” mechanism involving transfer of abnormal tau seeds...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Acta Neuropathol Commun
Main Authors: Mudher, Amrit, Colin, Morvane, Dujardin, Simon, Medina, Miguel, Dewachter, Ilse, Naini, Seyedeh Maryam Alavi, Mandelkow, Eva-Maria, Mandelkow, Eckhard, Buée, Luc, Goedert, Michel, Brion, Jean-Pierre
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735872/
https://ncbi.nlm.nih.gov/pubmed/29258615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0488-7
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