What is the evidence that tau pathology spreads through prion-like propagation?

Emerging experimental evidence suggests that the spread of tau pathology in the brain in Tauopathies reflects the propagation of abnormal tau species along neuroanatomically connected brain areas. This propagation could occur through a “prion-like” mechanism involving transfer of abnormal tau seeds...

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Detalles Bibliográficos
Publicado en:Acta Neuropathol Commun
Main Authors: Mudher, Amrit, Colin, Morvane, Dujardin, Simon, Medina, Miguel, Dewachter, Ilse, Naini, Seyedeh Maryam Alavi, Mandelkow, Eva-Maria, Mandelkow, Eckhard, Buée, Luc, Goedert, Michel, Brion, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
Assuntos:
Review
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735872/
https://ncbi.nlm.nih.gov/pubmed/29258615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0488-7
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