What is the evidence that tau pathology spreads through prion-like propagation?

Emerging experimental evidence suggests that the spread of tau pathology in the brain in Tauopathies reflects the propagation of abnormal tau species along neuroanatomically connected brain areas. This propagation could occur through a “prion-like” mechanism involving transfer of abnormal tau seeds...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Acta Neuropathol Commun
Egile Nagusiak: Mudher, Amrit, Colin, Morvane, Dujardin, Simon, Medina, Miguel, Dewachter, Ilse, Naini, Seyedeh Maryam Alavi, Mandelkow, Eva-Maria, Mandelkow, Eckhard, Buée, Luc, Goedert, Michel, Brion, Jean-Pierre
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2017
Gaiak:
Review
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735872/
https://ncbi.nlm.nih.gov/pubmed/29258615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0488-7
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