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From the prion-like propagation hypothesis to therapeutic strategies of anti-tau immunotherapy

The term “propagon” is used to define proteins that may transmit misfolding in vitro, in tissues or in organisms. Among propagons, misfolded tau is thought to be involved in the pathogenic mechanisms of various “tauopathies” that include Alzheimer's disease, progressive supranuclear palsy, and...

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Библиографические подробности
Опубликовано в: :Acta Neuropathol
Главные авторы: Colin, Morvane, Dujardin, Simon, Schraen-Maschke, Susanna, Meno-Tetang, Guy, Duyckaerts, Charles, Courade, Jean-Philippe, Buée, Luc
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Berlin Heidelberg 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942016/
https://ncbi.nlm.nih.gov/pubmed/31686182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-019-02087-9
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