From the prion-like propagation hypothesis to therapeutic strategies of anti-tau immunotherapy

The term “propagon” is used to define proteins that may transmit misfolding in vitro, in tissues or in organisms. Among propagons, misfolded tau is thought to be involved in the pathogenic mechanisms of various “tauopathies” that include Alzheimer's disease, progressive supranuclear palsy, and...

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Bibliographic Details
Published in:Acta Neuropathol
Main Authors: Colin, Morvane, Dujardin, Simon, Schraen-Maschke, Susanna, Meno-Tetang, Guy, Duyckaerts, Charles, Courade, Jean-Philippe, Buée, Luc
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2019
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942016/
https://ncbi.nlm.nih.gov/pubmed/31686182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-019-02087-9
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