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Targeting phospho-Ser422 by active Tau Immunotherapy in the THYTau22 mouse model: a suitable therapeutic approach

Recent data indicate that Tau immunotherapy may be relevant for interfering with neurofibrillary degeneration in Alzheimer disease and related disorders referred to as Tauopathies. The key question for immunotherapy is the choice of the epitope to target. Abnormal phosphorylation is a well-described...

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Détails bibliographiques
Auteurs principaux: Troquier, Laëticia, Caillierez, Raphaëlle, Burnouf, Sylvie, Fernandez-Gomez, Francisco J., Grosjean, Marie-Eve, Zommer, Nadège, Sergeant, Nicolas, Schraen-Maschke, Susanna, Blum, David, Buee, Luc
Format: Artigo
Langue:Inglês
Publié: Bentham Science Publishers 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637173/
https://ncbi.nlm.nih.gov/pubmed/22272619
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