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Targeting phospho-Ser422 by active Tau Immunotherapy in the THYTau22 mouse model: a suitable therapeutic approach

Recent data indicate that Tau immunotherapy may be relevant for interfering with neurofibrillary degeneration in Alzheimer disease and related disorders referred to as Tauopathies. The key question for immunotherapy is the choice of the epitope to target. Abnormal phosphorylation is a well-described...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Troquier, Laëticia, Caillierez, Raphaëlle, Burnouf, Sylvie, Fernandez-Gomez, Francisco J., Grosjean, Marie-Eve, Zommer, Nadège, Sergeant, Nicolas, Schraen-Maschke, Susanna, Blum, David, Buee, Luc
Format: Artigo
Sprache:Inglês
Veröffentlicht: Bentham Science Publishers 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637173/
https://ncbi.nlm.nih.gov/pubmed/22272619
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