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Tau Hyperphosphorylation and Oxidative Stress, a Critical Vicious Circle in Neurodegenerative Tauopathies?

Hyperphosphorylation and aggregation of the microtubule-associated protein tau in brain, are pathological hallmarks of a large family of neurodegenerative disorders, named tauopathies, which include Alzheimer's disease. It has been shown that increased phosphorylation of tau destabilizes tau-mi...

詳細記述

保存先:
書誌詳細
出版年:Oxid Med Cell Longev
主要な著者: Alavi Naini, Seyedeh Maryam, Soussi-Yanicostas, Nadia
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi Publishing Corporation 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630413/
https://ncbi.nlm.nih.gov/pubmed/26576216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/151979
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