Mitochondrial Oxidative Stress Causes Hyperphosphorylation of Tau

Age-related neurodegenerative disease has been mechanistically linked with mitochondrial dysfunction via damage from reactive oxygen species produced within the cell. We determined whether increased mitochondrial oxidative stress could modulate or regulate two of the key neurochemical hallmarks of A...

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Bibliografiska uppgifter
Huvudupphovsmän: Melov, Simon, Adlard, Paul A., Morten, Karl, Johnson, Felicity, Golden, Tamara R., Hinerfeld, Doug, Schilling, Birgit, Mavros, Christine, Masters, Colin L., Volitakis, Irene, Li, Qiao-Xin, Laughton, Katrina, Hubbard, Alan, Cherny, Robert A., Gibson, Brad, Bush, Ashley I.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2007
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1888726/
https://ncbi.nlm.nih.gov/pubmed/17579710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000536
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