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Hyperphosphorylation-Induced Tau Oligomers
In normal adult brain the microtubule associated protein (MAP) tau contains 2–3 phosphates per mol of the protein and at this level of phosphorylation it is a soluble cytosolic protein. The normal brain tau interacts with tubulin and promotes its assembly into microtubules and stabilizes these fibri...
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Main Authors: | , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Frontiers Media S.A.
2013
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3744035/ https://ncbi.nlm.nih.gov/pubmed/23966973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2013.00112 |
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