Intranasal insulin prevents anesthesia-induced hyperphosphorylation of tau in 3xTg-AD mice

Background: It is well documented that elderly individuals are at increased risk of cognitive decline after anesthesia. General anesthesia is believed to be a risk factor for Alzheimer’s disease (AD). Recent studies suggest that anesthesia may increase the risk for cognitive decline and AD through p...

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Bibliographic Details
Main Authors: Chen, Yanxing, Run, Xiaoqin, Liang, Zhihou, Zhao, Yang, Dai, Chun-ling, Iqbal, Khalid, Liu, Fei, Gong, Cheng-Xin
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2014
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038959/
https://ncbi.nlm.nih.gov/pubmed/24910612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2014.00100
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