A non-transgenic mouse model (icv-STZ mouse) of Alzheimer’s disease: Similarities to and differences from the transgenic model (3xTg-AD mouse)

Alzheimer’s disease (AD) can be divided into sporadic AD (SAD) and familial AD (FAD). Most AD cases are sporadic and result from multiple etiologic factors, including environmental, genetic and metabolic factors, whereas FAD is caused by mutations in the presenilins or amyloid-β (Aβ) precursor prote...

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Detalhes bibliográficos
Main Authors: Chen, Yanxing, Liang, Zhihou, Blanchard, Julie, Dai, Chun-Ling, Sun, Shenggang, Lee, Moon H., Grundke-Iqbal, Inge, Iqbal, Khalid, Liu, Fei, Gong, Cheng-Xin
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582864/
https://ncbi.nlm.nih.gov/pubmed/23150171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-012-8375-5
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