A non-transgenic mouse model (icv-STZ mouse) of Alzheimer’s disease: Similarities to and differences from the transgenic model (3xTg-AD mouse)

Alzheimer’s disease (AD) can be divided into sporadic AD (SAD) and familial AD (FAD). Most AD cases are sporadic and result from multiple etiologic factors, including environmental, genetic and metabolic factors, whereas FAD is caused by mutations in the presenilins or amyloid-β (Aβ) precursor prote...

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Autors principals: Chen, Yanxing, Liang, Zhihou, Blanchard, Julie, Dai, Chun-Ling, Sun, Shenggang, Lee, Moon H., Grundke-Iqbal, Inge, Iqbal, Khalid, Liu, Fei, Gong, Cheng-Xin
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582864/
https://ncbi.nlm.nih.gov/pubmed/23150171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-012-8375-5
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