A non-transgenic mouse model (icv-STZ mouse) of Alzheimer’s disease: Similarities to and differences from the transgenic model (3xTg-AD mouse)

Alzheimer’s disease (AD) can be divided into sporadic AD (SAD) and familial AD (FAD). Most AD cases are sporadic and result from multiple etiologic factors, including environmental, genetic and metabolic factors, whereas FAD is caused by mutations in the presenilins or amyloid-β (Aβ) precursor prote...

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Hlavní autoři: Chen, Yanxing, Liang, Zhihou, Blanchard, Julie, Dai, Chun-Ling, Sun, Shenggang, Lee, Moon H., Grundke-Iqbal, Inge, Iqbal, Khalid, Liu, Fei, Gong, Cheng-Xin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582864/
https://ncbi.nlm.nih.gov/pubmed/23150171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-012-8375-5
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