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Intracerebroventricular streptozotocin exacerbates Alzheimer-like changes of 3xTg-AD mice()

Alzheimer’s disease (AD) involves several possible molecular mechanisms, including impaired brain insulin signaling and glucose metabolism. To investigate the role of metabolic insults in AD, we injected streptozotocin (STZ), a diabetogenic compound if used in the periphery, into the lateral ventric...

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Detalhes bibliográficos
Main Authors: Chen, Yanxing, Liang, Zhihou, Tian, Zhu, Blanchard, Julie, Dai, Chun-ling, Chalbot, Sonia, Iqbal, Khalid, Liu, Fei, Gong, Cheng-Xin
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948211/
https://ncbi.nlm.nih.gov/pubmed/23996345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-013-8539-y
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