Impaired Spatial Reorientation in the 3xTg-AD Mouse Model of Alzheimer’s Disease

In early Alzheimer’s disease (AD) spatial navigation is impaired; however, the precise cause of this impairment is unclear. Recent evidence suggests that getting lost is one of the first impairments to emerge in AD. It is possible that getting lost represents a failure to use distal cues to get orie...

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Pubblicato in:Sci Rep
Autori principali: Stimmell, Alina C., Baglietto-Vargas, David, Moseley, Shawn C., Lapointe, Valérie, Thompson, Lauren M., LaFerla, Frank M., McNaughton, Bruce L., Wilber, Aaron A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361963/
https://ncbi.nlm.nih.gov/pubmed/30718609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37151-z
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