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p-Tau immunotherapy reduces soluble and insoluble tau in aged 3xTg-AD mice

Alzheimer’s disease (AD) is a proteinopathy characterized by the accumulation of β-amyloid (Aβ) and tau. To date, clinical trials indicate that Aβ immunotherapy does not improve cognition. Consequently, it is critical to modulate other aspects of AD pathology. As such, tau represents an excellent ta...

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Detalles Bibliográficos
Publicado en:Neurosci Lett
Autores principales: Walls, Ken C., Ager, Rahasson R., Vasilevko, Vitaly, Cheng, Dave, Medeiros, Rodrigo, LaFerla, Frank M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437620/
https://ncbi.nlm.nih.gov/pubmed/24887583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2014.05.047
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