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Genetic Knockdown of Brain-Derived Neurotrophic Factor in 3xTg-AD Mice Does Not Alter Aβ or Tau Pathology

Brain-derived neurotrophic factor (BDNF) is a neurotrophin critically involved in cell survival, synaptic plasticity, and memory. BDNF has recently garnered significant attention as a potential therapeutic target for neurodegenerative diseases such as Alzheimer disease (AD), but emerging evidence su...

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מידע ביבליוגרפי
Main Authors: Castello, Nicholas A., Green, Kim N., LaFerla, Frank M.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411687/
https://ncbi.nlm.nih.gov/pubmed/22870188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039566
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