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p-Tau immunotherapy reduces soluble and insoluble tau in aged 3xTg-AD mice

Alzheimer’s disease (AD) is a proteinopathy characterized by the accumulation of β-amyloid (Aβ) and tau. To date, clinical trials indicate that Aβ immunotherapy does not improve cognition. Consequently, it is critical to modulate other aspects of AD pathology. As such, tau represents an excellent ta...

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Bibliografski detalji
Izdano u:Neurosci Lett
Glavni autori: Walls, Ken C., Ager, Rahasson R., Vasilevko, Vitaly, Cheng, Dave, Medeiros, Rodrigo, LaFerla, Frank M.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437620/
https://ncbi.nlm.nih.gov/pubmed/24887583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2014.05.047
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