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p-Tau immunotherapy reduces soluble and insoluble tau in aged 3xTg-AD mice
Alzheimer’s disease (AD) is a proteinopathy characterized by the accumulation of β-amyloid (Aβ) and tau. To date, clinical trials indicate that Aβ immunotherapy does not improve cognition. Consequently, it is critical to modulate other aspects of AD pathology. As such, tau represents an excellent ta...
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| Publicado en: | Neurosci Lett |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4437620/ https://ncbi.nlm.nih.gov/pubmed/24887583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2014.05.047 |
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