Age-dependent sexual dimorphisms in cognition and stress response in the 3xTg-AD mice

We sought to determine if sex impacts the cognitive and neuropathological phenotype of the 3xTg-AD mice. We find that male and female 3xTg-AD mice show comparable impairments on Morris water maze (MWM) and inhibitory avoidance (IA) at 4 months. Shortly thereafter, however, the cognitive performance...

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Bibliografiske detaljer
Main Authors: Clinton, Lani K., Billings, Lauren M., Green, Kim N., Caccamo, Antonella, Ngo, Jerry, Oddo, Salvatore, McGaugh, James L., LaFerla, Frank M.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756084/
https://ncbi.nlm.nih.gov/pubmed/17659878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2007.06.013
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