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Temporal and regional progression of Alzheimer’s disease‐like pathology in 3xTg‐AD mice

Accumulation of amyloid‐β (Aβ) and fibrillary tangles, as well as neuroinflammation and memory loss, are hallmarks of Alzheimer’s disease (AD). After almost 15 years from their generation, 3xTg‐AD mice are still one of the most used transgenic models of AD. Converging evidence indicates that the phe...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Belfiore, Ramona, Rodin, Alexis, Ferreira, Eric, Velazquez, Ramon, Branca, Caterina, Caccamo, Antonella, Oddo, Salvatore
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351836/
https://ncbi.nlm.nih.gov/pubmed/30488653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12873
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