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Temporal and regional progression of Alzheimer’s disease‐like pathology in 3xTg‐AD mice

Accumulation of amyloid‐β (Aβ) and fibrillary tangles, as well as neuroinflammation and memory loss, are hallmarks of Alzheimer’s disease (AD). After almost 15 years from their generation, 3xTg‐AD mice are still one of the most used transgenic models of AD. Converging evidence indicates that the phe...

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Dettagli Bibliografici
Pubblicato in:Aging Cell
Autori principali: Belfiore, Ramona, Rodin, Alexis, Ferreira, Eric, Velazquez, Ramon, Branca, Caterina, Caccamo, Antonella, Oddo, Salvatore
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351836/
https://ncbi.nlm.nih.gov/pubmed/30488653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12873
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