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Hyperphosphorylation-Induced Tau Oligomers

In normal adult brain the microtubule associated protein (MAP) tau contains 2–3 phosphates per mol of the protein and at this level of phosphorylation it is a soluble cytosolic protein. The normal brain tau interacts with tubulin and promotes its assembly into microtubules and stabilizes these fibri...

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Autori principali: Iqbal, Khalid, Gong, Cheng-Xin, Liu, Fei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744035/
https://ncbi.nlm.nih.gov/pubmed/23966973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2013.00112
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