Pathological Tau From Alzheimer’s Brain Induces Site-Specific Hyperphosphorylation and SDS- and Reducing Agent-Resistant Aggregation of Tau in vivo

Neurofibrillary tangles (NFTs) made up of hyperphosphorylated tau are a histopathological hallmark of Alzheimer’s disease (AD) and related tauopathies. Hyperphosphorylation of tau is responsible for its loss of normal physiological function, gain of toxicity and its aggregation to form NFTs. Injecti...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Front Aging Neurosci
Main Authors: Miao, Jin, Shi, Ruirui, Li, Longfei, Chen, Feng, Zhou, Yan, Tung, Yunn Chyn, Hu, Wen, Gong, Cheng-Xin, Iqbal, Khalid, Liu, Fei
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411797/
https://ncbi.nlm.nih.gov/pubmed/30890929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2019.00034
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker