Pathological Tau From Alzheimer’s Brain Induces Site-Specific Hyperphosphorylation and SDS- and Reducing Agent-Resistant Aggregation of Tau in vivo

Neurofibrillary tangles (NFTs) made up of hyperphosphorylated tau are a histopathological hallmark of Alzheimer’s disease (AD) and related tauopathies. Hyperphosphorylation of tau is responsible for its loss of normal physiological function, gain of toxicity and its aggregation to form NFTs. Injecti...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Front Aging Neurosci
Huvudupphovsmän: Miao, Jin, Shi, Ruirui, Li, Longfei, Chen, Feng, Zhou, Yan, Tung, Yunn Chyn, Hu, Wen, Gong, Cheng-Xin, Iqbal, Khalid, Liu, Fei
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2019
Ämnen:
Neuroscience
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411797/
https://ncbi.nlm.nih.gov/pubmed/30890929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2019.00034
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk