Učitavanje...

Activation of Asparaginyl Endopeptidase Leads to Tau Hyperphosphorylation in Alzheimer Disease

Neurofibrillary pathology of abnormally hyperphosphorylated Tau is a key lesion of Alzheimer disease and other tauopathies, and its density in the brain directly correlates with dementia. The phosphorylation of Tau is regulated by protein phosphatase 2A, which in turn is regulated by inhibitor 2, I(...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Basurto-Islas, Gustavo, Grundke-Iqbal, Inge, Tung, Yunn Chyn, Liu, Fei, Iqbal, Khalid
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682549/
https://ncbi.nlm.nih.gov/pubmed/23640887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.446070
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!