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Disruption of microtubule network by Alzheimer abnormally hyperphosphorylated tau

Hyperphosphorylated tau has long been proposed as the key molecule disrupting normal neuronal microtubule dynamics and leading to neurofibrillary degeneration in Alzheimer disease. Here we provide a direct evidence of hyperphosphorylated tau-induced disruption of microtubule network. Using Nocodozol...

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Detaylı Bibliyografya
Asıl Yazarlar: Li, Bin, Chohan, Muhammad Omar, Grundke-Iqbal, Inge, Iqbal, Khalid
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191942/
https://ncbi.nlm.nih.gov/pubmed/17372746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-007-0207-8
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