Chronic cerebral hypoperfusion causes decrease of O-GlcNAcylation, hyperphosphorylation of tau and behavioral deficits in mice

Chronic cerebral hypoperfusion (CCH) is one of the causes of vascular dementia (VaD) and is also an etiological factor for Alzheimer’s disease (AD). However, how CCH causes cognitive impairment and contributes to Alzheimer’s pathology is poorly understood. Here we produced a mouse model of CCH by un...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Zhao, Yang, Gu, Jin-hua, Dai, Chun-ling, Liu, Qun, Iqbal, Khalid, Liu, Fei, Gong, Cheng-Xin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2014
Konular:
Neuroscience
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918671/
https://ncbi.nlm.nih.gov/pubmed/24575038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2014.00010
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