ANGI-14. EPIGENETIC REACTIVATION OF BAI1 SUPPRESSES TUMOR INVASION BY PREVENTING TGFβ1-INDUCED MESENCHYMAL SWITCH IN GLIOBLASTOMA

nork Osuka, Satoru, Yang, Liquan, Zhu, Dan, Devi, Narra, Van Meir, Erwin
Argitaratua izan da Neuro Oncol (2018)

PDTM-12. ADGRB3 IS EPIGENETICALLY SILENCED IN WNT-MEDULLOBLASTOMA AND ITS REACTIVATION HAS THERAPEUTIC BENEFITS

nork Bhattacharya, Debanjan, Zhu, Dan, Osuka, Satoru, Kaluz, Stefan, Devi, Narra, Van Meir, Erwin
Argitaratua izan da Neuro Oncol (2019)

Examining the Structure-activity Relationship of Benzopyran-based inhibitors of the Hypoxia Inducible Factor-1 Pathway

nork Ferguson, Jalisa, De Los Santos, Zeus, Devi, Narra, Van Meir, Erwin, Zingales, Sarah, Wang, Binghe
Argitaratua izan da Bioorg Med Chem Lett (2017)

Structure–activity relationship of 2,2-dimethyl-2H-chromene based arylsulfonamide analogs of 3,4-dimethoxy-N-[(2,2-dimethyl-2H-chromen-6-yl)methyl]-N-phenylbenzenesulfonamide, a no...

nork Mun, Jiyoung, Jabbar, Adnan Abdul, Devi, Narra Sarojini, Liu, Yuan, Van Meir, Erwin G., Goodman, Mark M.
Argitaratua izan da Bioorg Med Chem (2012)

EZH2 targeting in medulloblastoma reduces tumor growth through epigenetic reactivation of the BAI1/p53 tumor suppressor pathway

nork Zhang, Hanwen, Zhu, Dan, Zhang, Zhaobin, Kaluz, Stefan, Yu, Bing, Devi, Narra S., Olson, Jeffrey J., Van Meir, Erwin G.
Argitaratua izan da Oncogene (2019)

BAP1 is a tumor suppressor that requires deubiquitinating activity and nuclear localization

nork Ventii, Karen H., Devi, Narra S., Friedrich, Kenneth L., Chernova, Tatiana A., Tighiouart, Mourad, Van Meir, Erwin G., Wilkinson, Keith D.
Argitaratua 2008

Design and Synthesis of Novel Small-molecule Inhibitors of the Hypoxia Inducible Factor Pathway

nork Mooring, Suazette Reid, Jin, Hui, Devi, Narra S., Jabbar, Adnan A., Kaluz, Stefan, Liu, Yuan, Van Meir, Erwin G., Wang, Binghe
Argitaratua 2011

A proprotein convertase/MMP-14 proteolytic cascade releases a novel 40 kDa vasculostatin from tumor suppressor BAI1

nork Cork, Sarah M., Kaur, Balveen, Devi, Narra S., Cooper, Lee, Saltz, Joel H., Sandberg, Eric M., Kaluz, Stefan, Van Meir, Erwin G.
Argitaratua 2012

Targeted Cancer Gene Therapy Using a Hypoxia Inducible Factor–Dependent Oncolytic Adenovirus Armed with Interleukin-4

nork Post, Dawn E., Sandberg, Eric M., Kyle, Michele M., Devi, Narra Sarojini, Brat, Daniel J., Xu, Zhiheng, Tighiouart, Mourad, Van Meir, Erwin G.
Argitaratua 2007

A NOVEL P53 BYSTANDER EFFECT INDUCES GLIOBLASTOMA CELL DEATH THROUGH A GLYCOSYLATION-DEPENDENT MECHANISM

nork Van Meir, Erwin G., Lee, Sok-Hyong, Khwaja, Fatima W., Zerrouqi, Abdessamad, Zhang, Zhaobin, Olson, Jeffrey J., Kaluzova, Milota, Hadjipanayis, Costas G., Devi, Narra S.
Argitaratua 2014

Sulfonamides as a New Scaffold for Hypoxia Inducible Factor Pathway Inhibitors

nork Tan, Chalet, de Noronha, Rita, Devi, Narra S., Jabbar, Adnan A., Kaluz, Stefan, Liu, Yuan, Mooring, Suazette Reid, Nicolaou, K.C., Wang, Binghe, Van Meir, Erwin G.
Argitaratua 2011

Design and in vitro activities of N-alkyl-N-[(8-R-2,2-dimethyl-2H-chromen-6-yl)methyl]heteroarylsulfonamides, novel small molecule Hypoxia Inducible Factor-1 (HIF-1) pathway inhibi...

nork Mun, Jiyoung, Jabbar, Adnan Abdul, Devi, Narra Sarojini, Yin, Shaoman, Wang, Yingzhe, Tan, Chalet, Culver, Deborah, Snyder, James P., Van Meir, Erwin G., Goodman, Mark M.
Argitaratua 2012

Arylsulfonamide 64B inhibits hypoxia/HIF-induced expression of c-Met and CXCR4 and reduces primary tumor growth and metastasis of uveal melanoma

nork Dong, Lei, You, Shuo, Zhang, Qing, Osuka, Satoru, Devi, Narra S, Kaluz, Stefan, Holmes, Jalisa Nicole, Yang, Hua, Chen, Guoliang, Wang, Binghe, Grossniklaus, Hans E., Van Meir, Erwin G.
Argitaratua izan da Clin Cancer Res (2018)

A Chimeric Signal Peptide-Galectin-3 Conjugate Induces Glycosylation-Dependent Cancer Cell-Specific Apoptosis

nork Lee, Sok-Hyong, Rehman, Fatima K., Tyler, Kari, Yu, Bing, Zhang, Zhaobin, Osuka, Satoru, Zerrouqi, Abdessamad, Kaluzova, Milota, Hadjipanayis, Costas G., Cummings, Richard D., Olson, Jeffrey J., Devi, Narra S., Van Meir, Erwin G.
Argitaratua izan da Clin Cancer Res (2020)

Binding Model for the Interaction of Anticancer Arylsulfonamides with the p300 Transcription Cofactor

nork Shi, Qi, Yin, Shaoman, Kaluz, Stefan, Ni, Nanting, Devi, Narra Sarojini, Mun, Jiyoung, Wang, Danzhu, Damera, Krishna, Chen, Weixuan, Burroughs, Sarah, Mooring, Suazette Reid, Goodman, Mark M., Van Meir, Erwin G., Wang, Binghe, Snyder, James P.
Argitaratua 2012

Vasculostatin inhibits intracranial glioma growth and negatively regulates in vivo angiogenesis through a CD36-dependent mechanism

nork Kaur, Balveen, Cork, Sarah M, Sandberg, Eric M, Devi, Narra S, Zhang, Zhaobin, Klenotic, Philip A, Febbraio, Maria, Shim, Hyunsuk, Mao, Hui, Tucker-Burden, Carol, Silverstein, Roy L, Brat, Daniel J, Olson, Jeffrey J, Van Meir, Erwin G
Argitaratua 2009

Selective Detection of the D-enantiomer of 2-Hydroxyglutarate in the CSF of Glioma Patients with Mutated Isocitrate Dehydrogenase

nork Kalinina, Juliya, Ahn, Jun, Devi, Narra S., Wang, Liya, Li, Yuancheng, Olson, Jeffrey J., Glantz, Michael, Smith, Thomas, Kim, Ella L., Giese, Alf, Jensen, Randy L., Chen, Clark C., Carter, Bob S., Mao, Hui, He, Miao, Van Meir, Erwin G.
Argitaratua izan da Clin Cancer Res (2016)

Arylsulfonamide KCN1 inhibits in vivo glioma growth and interferes with HIF signaling by disrupting HIF-1α interaction with co-factors p300/CBP

nork Yin, Shaoman, Kaluz, Stefan, Devi, Narra S., Jabbar, Adnan A., de Noronha, Rita G., Mun, Jiyoung, Zhang, Zhaobin, Boreddy, Purushotham R., Wang, Wei, Wang, Zhibo, Abbruscato, Thomas, Chen, Zhengjia, Olson, Jeffrey J., Zhang, Ruiwen, Goodman, Mark M., Nicolaou, K.C., Van Meir, Erwin G.
Argitaratua 2012

BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-mediated Degradation

nork Zhu, Dan, Osuka, Satoru, Zhang, Zhaobin, Reichert, Zachery R., Yang, Liquan, Kanemura, Yonehiro, Jiang, Ying, You, Shuo, Zhang, Hanwen, Devi, Narra S., Bhattacharya, Debanjan, Takano, Shingo, Gillespie, G. Yancey, Macdonald, Tobey, Tan, Chalet, Nishikawa, Ryo, Nelson, William G., Olson, Jeffrey J., Van Meir, Erwin G.
Argitaratua izan da Cancer Cell (2018)

Tyr-phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate pyruvate dehydrogenase complex

nork Fan, Jun, Shan, Changliang, Kang, Hee-Bum, Elf, Shannon, Xie, Jianxin, Tucker, Meghan, Gu, Ting-Lei, Aguiar, Mike, Lonning, Scott, Chen, Huaibin, Mohammadi, Moosa, Britton, Laura-Mae P., Garcia, Benjamin A., Aleckovic, Masa, Kang, Yibin, Kaluz, Stefan, Devi, Narra, Van Meir, Erwin, Hitosugi, Taro, Seo, Jae Ho, Lonial, Sagar, Gaddh, Manila, Arellano, Martha, Khoury, Hanna J., Khuri, Fadlo R., Boggon, Titus J., Kang, Sumin, Chen, Jing
Argitaratua 2014