BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-mediated Degradation

Adhesion G-protein coupled receptors (ADGRs) encompass 33 human transmembrane proteins with long N-termini involved in cell-cell and cell-matrix interactions. We show the ADGRB1 gene, which encodes Brain-specific angiogenesis inhibitor 1 (BAI1), is epigenetically silenced in medulloblastomas (MBs) t...

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Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Zhu, Dan, Osuka, Satoru, Zhang, Zhaobin, Reichert, Zachery R., Yang, Liquan, Kanemura, Yonehiro, Jiang, Ying, You, Shuo, Zhang, Hanwen, Devi, Narra S., Bhattacharya, Debanjan, Takano, Shingo, Gillespie, G. Yancey, Macdonald, Tobey, Tan, Chalet, Nishikawa, Ryo, Nelson, William G., Olson, Jeffrey J., Van Meir, Erwin G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002773/
https://ncbi.nlm.nih.gov/pubmed/29894688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.05.006
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