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PDTM-27. EPIGENETIC LOSS OF BAI1 EXPRESSION IN CEREBELLAR GRANULE NEURON PRECURSORS INACTIVATES THE p53 TUMOR SUPPRESSOR AND FACILITATES MEDULLOBLASTOMA FORMATION IN THE CEREBELLUM
Adhesion G-protein coupled receptors (ADGRs) are transmembrane proteins involved in cell-cell/matrix interactions. We show ADGRB1 gene, which encodes Brain-specific angiogenesis inhibitor 1 (BAI1), is epigenetically silenced in human medulloblastomas through a methyl-CpG binding protein 2 (MBD2)-dep...
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| 出版年: | Neuro Oncol |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6217668/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.868 |
| タグ: |
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