PDTM-12. ADGRB3 IS EPIGENETICALLY SILENCED IN WNT-MEDULLOBLASTOMA AND ITS REACTIVATION HAS THERAPEUTIC BENEFITS

Medulloblastoma (MB) are the most aggressive primary malignant brain tumors in children and are classified into four major molecular subgroups. WNT-MB is characterized by an activated WNT signature and has relatively better prognosis with treatment. However, young WNT-MB patients who survive after c...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Bhattacharya, Debanjan, Zhu, Dan, Osuka, Satoru, Kaluz, Stefan, Devi, Narra, Van Meir, Erwin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Pediatric Tumors
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847088/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.788
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