ANGI-14. EPIGENETIC REACTIVATION OF BAI1 SUPPRESSES TUMOR INVASION BY PREVENTING TGFβ1-INDUCED MESENCHYMAL SWITCH IN GLIOBLASTOMA

Glioblastoma (GBM) is the most common and lethal type of malignant brain tumor in adults. GBM cells are highly invasive and diffusely infiltrate throughout the brain, which strongly restricts multimodal therapies. Acquiring a better knowledge of molecular defects underlying GBM invasion is essential...

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Опубликовано в: :Neuro Oncol
Главные авторы: Osuka, Satoru, Yang, Liquan, Zhu, Dan, Devi, Narra, Van Meir, Erwin
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216746/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.115
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