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Sulfonamides as a New Scaffold for Hypoxia Inducible Factor Pathway Inhibitors
Solid tumors generally grow under hypoxic conditions, a pathophysiological change, which activates the expression of genes responsible for malignant, aggressive, and treatment-refractory properties. Hypoxia inducible factor (HIF) is the chief transcription factor regulating hypoxia-driven gene expre...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3292863/ https://ncbi.nlm.nih.gov/pubmed/21831638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.06.099 |
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