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Design and synthesis of benzopyran-based inhibitors of the hypoxia-inducible factor-1 pathway with improved water solubility

While progress has been made in treating cancer, cytotoxic chemotherapeutic agents are still the most widely used drugs and are associated with severe side-effects. Drugs that target unique molecular signalling pathways are needed for treating cancer with low or no intrinsic toxicity to normal cells...

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Podrobná bibliografie
Vydáno v:J Enzyme Inhib Med Chem
Hlavní autoři: Ferguson, Jalisa H., De Los Santos, Zeus, Devi, Saroja N., Kaluz, Stefan, Van Meir, Erwin G., Zingales, Sarah K., Wang, Binghe
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009948/
https://ncbi.nlm.nih.gov/pubmed/28766956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1347784
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