Design and synthesis of benzopyran-based inhibitors of the hypoxia-inducible factor-1 pathway with improved water solubility

While progress has been made in treating cancer, cytotoxic chemotherapeutic agents are still the most widely used drugs and are associated with severe side-effects. Drugs that target unique molecular signalling pathways are needed for treating cancer with low or no intrinsic toxicity to normal cells...

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Udgivet i:J Enzyme Inhib Med Chem
Main Authors: Ferguson, Jalisa H., De Los Santos, Zeus, Devi, Saroja N., Kaluz, Stefan, Van Meir, Erwin G., Zingales, Sarah K., Wang, Binghe
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009948/
https://ncbi.nlm.nih.gov/pubmed/28766956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1347784
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