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Binding Model for the Interaction of Anticancer Arylsulfonamides with the p300 Transcription Cofactor
[Image: see text] Hypoxia inducible factors (HIFs) are transcription factors that activate expression of multiple gene products and promote tumor adaptation to a hypoxic environment. To become transcriptionally active, HIFs associate with cofactors p300 or CBP. Previously, we found that arylsulfonam...
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| Autors principals: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American
Chemical Society
2012
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4056939/ https://ncbi.nlm.nih.gov/pubmed/24936238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300042k |
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