Binding Model for the Interaction of Anticancer Arylsulfonamides with the p300 Transcription Cofactor

[Image: see text] Hypoxia inducible factors (HIFs) are transcription factors that activate expression of multiple gene products and promote tumor adaptation to a hypoxic environment. To become transcriptionally active, HIFs associate with cofactors p300 or CBP. Previously, we found that arylsulfonam...

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Detalhes bibliográficos
Main Authors: Shi, Qi, Yin, Shaoman, Kaluz, Stefan, Ni, Nanting, Devi, Narra Sarojini, Mun, Jiyoung, Wang, Danzhu, Damera, Krishna, Chen, Weixuan, Burroughs, Sarah, Mooring, Suazette Reid, Goodman, Mark M., Van Meir, Erwin G., Wang, Binghe, Snyder, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056939/
https://ncbi.nlm.nih.gov/pubmed/24936238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300042k
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